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HQO鍏锋湁鍏╁��(g猫)婵�鐧�(f膩)鑸囩浉鎳�(y墨ng)鐧�(f膩)灏勬尝闀凤紝涓�鍊�(g猫)绀鸿工绶氱矑楂�锛屼竴鍊�(g猫)绀鸿工鑷櫖婧堕叾楂旓紝閫氶亷鍏╁��(g猫)娉㈤暦鐨勮畩鍖栦締闂¤堪鑷櫖娴佺▼銆傚拰宸叉湁甯歌(gu墨)鑷櫖妾㈡脯鏂规硶鐩告瘮锛屽畠鍏锋湁濡備笅鍎�(y艒u)鍕細鈶犳ǎ鍝佸埗鍌欑啊鍠�锛涒憽鎿嶄綔姝ラ灏�锛涒憿鐗圭暟鎬ф寚绀虹窔绮掗珨琚櫖鍒拌嚜鍣憾閰堕珨褰㈡垚鐨勯亷绋�锛屼笖鑳界壒鐣版�ф寚绀哄眬閮ㄧ窔绮掗珨鐨勮鍣�锛涒懀鎵�闇�鐩告噳(y墨ng)鑰楁潗鍙婂伐鍏疯純灏�銆�[1]
鍦栦竴锛氭帰閲�HQO鍜�HQO绀鸿工娲荤窗(x矛)鑳炵窔绮掗珨鑷櫖閬庣▼鍘熺悊鍦�
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鐢�(ch菐n)鍝佺法铏�
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鐢�(ch菐n)鍝�鍚嶇ū
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绨＄ū
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CAS
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绲�(ji茅)妲�(g貌u)寮�
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2668725
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2,6-闆欙紙2-锛�3,3-浜岀敳鍩�-1-涓欏熀 - 浜屾矮鍚插摎-2-浜炲熀锛変簽涔欏熀锛� - 鐠�(hu谩n)宸遍叜
2,6-Bi(2-(3,3-dimethyl-1-propylindolin-2-ylidene)ethylidene)-cyclohexanone
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HQO
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1442645-34-2
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鐢�(ch菐n)鍝佷娇鐢ㄨ鏄庯細
1銆佺窗(x矛)鑳炵殑鍩归(y菐ng)锛屽皣绱�(x矛)鑳炵ó妞嶄簬鍏辫仛鐒﹀煿椁�(y菐ng)鐨夸腑锛屾牴鎿�(j霉)涓嶅悓瀵�(sh铆)椹�(y脿n)闇�瑕佺ó妞嶇浉鎳�(y墨ng)绱�(x矛)鑳炲瘑搴﹀強鍩归(y菐ng)鐩告噳(y墨ng)鏅�(sh铆)闁�銆�
2銆佽獦灏�(d菐o)鑷櫖銆佺窗(x矛)鑳炴煋鑹插拰鍏辫仛鐒︽垚鍍�銆傞仼鐣�(d膩ng)姊濅欢瑾樺皫(d菐o)鑷櫖锛堝鐒¤娓呭煿椁�(y菐ng)鍩�銆�PBS鎴栬�呯窗(x矛)鑳炶嚜鍣縺娲诲姂铏曠悊绛夛級锛�HQO锛�10 μM锛変簬鐒¤娓呭煿椁�(y菐ng)鍩轰腑鍔犲叆鍩归(y菐ng)鐨夸腑37鈩冨鑲�10 min锛�PBS娲楁粚涓�鍒颁笁娆�锛屽叡鑱氱劍鎴愬儚銆�559 nm婵�鐧�(f膩)锛�570-610 nm鐧�(f膩)灏勬尝闀风偤绀鸿工姝ｅ父绶氱矑楂旂殑鐔掑厜锛�635 nm婵�鐧�(f膩)锛�650-730 nm鐧�(f膩)灏勬尝闀风偤绀鸿工鑷櫖婧堕叾楂旂殑鐔掑厜銆�
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鐢�(ch菐n)鍝�鍚嶇ū
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CAS
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绲�(ji茅)妲�(g貌u)寮�
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2668724
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2,9-闆�[4-锛�4-鐢插熀鍝屽棯-1-鍩猴級鑻箼鐑熀]-1,10 - 鑿插挴鍟�
2,9-Bis[4-(4-methylpi-perazin-1-yl)styryl]-1,10-phenanthroline
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1792998-33-4
|
|
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2668726
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N-宸遍吀鍩�-4H-1,2,4-涓夋爱鍞�(1,5-a)浜屾爱闆滅挵(hu谩n)-1,8-钀橀叞浜炶兒
3,9-Dihydro-1,3-dioxopyrido[3,4,5-gh][1,2,4]triazolo[1,5-a]perimidine-2(1h)-hexanoic acid
|
1359819-97
|
|
|
2668727
|
CSTS
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N/A
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433521
|
D-鐔掑厜绱犻墍楣�
D-Luciferin potassium salt
|
115144-35-9
|
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|
102273
|
2,3-浜屾皑鍩鸿悩
2,3-Diaminonaphthalene
|
771-97-1
|
|
|
2668723
|
9-鐢插熀-3,6-闆�[5-锛�4-鐢插熀鍝屽棯-1-鍩猴級-1H-鑻苟[d]鍜攽-2-鍩�] -9H-鍜斿攽
9-Methyl-3,6-bis[5-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl]-9H-carbazole
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1514901-89-3
|
|
|
227585
|
閯拌嫰浜岀敳閱�
o-Phthalaldehyde
|
643-79-8
|
|
鐩搁棞(gu膩n)鏂囩嵒(xi脿n)
[1] Ying Liu, Jin Zhou, Linlin Wang, Xiaoxiao Hu, Xiangjun Liu, Meirong Liu, Zehui Cao, Dihua Shangguan and Weihong Tan. A Cyanine Dye to Probe Mitophagy: Simultaneous Detection of Mitochondria and Autolysosomes in Live Cells, J. Am. Chem. Soc., 2016, 138 (38), pp 12368–12374, DOI: 10.1021/jacs.6b04048锛�
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